Search results for "Cardiovascular disease burden"

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APOC-III: a Gatekeeper in Controlling Triglyceride Metabolism

2023

Abstract Purpose of Review Apolipoprotein C-III (ApoC-III) is a widely known player in triglyceride metabolism, and it has been recently recognized as a polyhedric factor which may regulate several pathways beyond lipid metabolism by influencing cardiovascular, metabolic, and neurological disease risk. This review summarizes the different functions of ApoC-III and underlines the recent findings related to its multifaceted pathophysiological role. Recent Findings The role of ApoC-III has been implicated in HDL metabolism and in the development of atherosclerosis, inflammation, and ER stress in endothelial cells. ApoC-III has been recently considered an important player in insulin resistance …

Cardiovascular disease burdenPost prandial lipemiaTriglyceride-rich lipoproteins (TRLs).Cardiology and Cardiovascular MedicineApoC-III

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